Custom Peptides
Cayman Chemical PLP139-151trIfluoroaceta 10mg
An encephalitogenic peptide; induces the formation of inflammatory foci, axonal injury, and demyelination in the spinal cord, as well as motor deficits in mice at 150 UG/animal; commonly used to induce EAE in mice
Cayman Chemical Estron3GlucuronIdesodIum 10mg
A metabolite of 17β-estradiol; urinary levels peak approximately 36 hours prior to ovulation and have been used as a marker of fertility in women
Cayman Chemical IpsapIronhydrochlorIde 10mg
A partial agonist of serotonin 5-HT1A receptors (Ki = 10 nM in hippocampal membranes); reduces 5-HT release in rat ventral hippocampus in vivo; low doses decrease, while high doses increase, extracellular dopamine release in murine nucleus accumbens; extracellular dopamine levels in murine striatum increase following administration at concentrations >0.1 mg/kg; has anxiolytic effects in vivo, inhibiting foot shock-induced aggression and passive avoidance behavior in rats (ED50s = 2.2 and 0.5 mg/kg, respectively)
Cayman Chemical 9-keto Fluprostenol 10mg
9-keto Fluprostenol is an analog of PGE2 with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor.{1182} Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist.
Cayman Chemical PramlIntIdeacetAT hydrAT 10mg
An amylin analog; stimulates cAMP production in HEK293 cells expressing human AMY1a, AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89 nM, respectively); inhibits human islet amyloid polypeptide fibrilization in a concentration-dependent manner; reduces brain levels of Aβ40 and increases spontaneous alternation in the Y-maze in the Tg2576 transgenic mouse model of Alzheimer's disease at 200 pg/kg
Cayman Chemical Decnoyl-L-carnItInchlorId 10mg
A derivative of L-carnitine; increases the formation of C24 fatty acid intermediates, as well as docosapentaenoic and docosahexaenoic acid in rat hepatocytes
Cayman Chemical 3hydroxy OctNIc ACD mthy 10mg
A hydroxy fatty acid methyl ester; a volatile compound and aromatic agent that has been found in pineapple, Yuzu, sudachi, and Kabosu sour citrus fruits, and human axillary sweat
Cayman Chemical S 2 4DInItrophenylGlutath 10mg
A substrate for glutathione-S-transferase with a kinetic dissociation constant of 7 µM; transported by MDR1 and MDR3
Cayman Chemical PrIstImerIn 10mg
A naturally occuring terpenoid that potently inhibits MAGL (IC50 = 93 nM); at 1 µM, significantly inhibits endogenous MAGL in isolated rat neurons
Cayman Chemical 3 4-EDMAhydrochlorIde 10mg
An analog of 3,4-MDMA that stimulates the release of serotonin and dopamine from rat brain synaptosomes at 1 µM
Cayman Chemical 5-fluoro ADBICA 10mg
A derivative of ADBICA featuring a fluorine atom added to the terminal carbon of the pentyl group; intended for forensic and research applications
Cayman Chemical trns-3-HydroxycotInIn 10mg
A product of CYP2A6 metabolism of the primary nicotine metabolite, cotinine; as a biomarker of nicotine metabolism